Glycogen storage diseases can be treated but cannot be cured. Yet. For Type
I glycogen storage disease, it focuses on correcting the metabolic changes in
the body by providing small, frequent feedings of uncooked cornstarch mixed in water,
or soy milk. Since cornstarch is digested slowly, it provides a steady release
of glucose. Maintenance of the blood glucose level could reverse all of the
physical and chemical signs of this disease.
In addition, most doctors would
restrict patients to consume certain sugars like sucrose (table sugar),
fructose (sugar from fruits), lactose and galactose (sugars found in milk), but
the degree of restriction is still being debated on.
Patients diagnosed with
GSD type Ib are required to take medication to increase the number of
neutrophils, a type of white blood cell that fights infection. This is to
reduce the risk that arises due to the weakening of the immune system.
Liver transplantation has also become a new option for some patients suffering from anemia as a result of their GSD, although the viability of this option for children is still debated upon.
In 2011, Dr David
Weinstein and Dr Cathryn Mah, of the University of Florida, began testing the
possibility of gene therapy for treating GSD Type Ia. Using canines as their
model for comparison; they administered two doses of gene therapy to a dog that
had the disease. Six weeks after therapy, the dog no longer relied on glucose
supplements. This discovery indeed offers much hope to patients out there who
see this as a final cure to their glycogen storage disorder.
Hi guys! (:
ReplyDeleteYour blog is really filled with concised information. It's interesting and easy to read.
It is effective in helping me learn more knowledge about this disease!
hey guys! I love the content that you guys have put up in this blog. It is concise and sufficient. Despite the highly wordy posts, it is pretty easy to understand the contents too! It provides a wide range of information. And i like how your introduction had an example because it helps me to visualize the whole concept. Good job! (:
ReplyDeleteVery interesting, and informative! Easy to understand just by reading and its nice how you the pictures are really engaging!
ReplyDeleteVery nice blog! :)
Hi! I like the way you present your blog information in an organised manner and the contents in your blog is comprehensive and it helps me to understand glycogen storage diseases that are outside the content of our lecture notes. :) Well-written!
ReplyDeleteI have a question regarding the diagnosis part:
Can this disease be diagnose even before birth, such as through the diagnosis of diseased gene sequence with the help of the human genome project?
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